The sustainable management of biogas slurry (BS) necessitates advanced technologies for efficient nutrient separation and recovery. While membrane processes show promise, their implementation is hindered by persistent challenges including membrane fouling, high energy consumption, and production of low-value mixed concentrates. To address these limitations, this study introduces a novel pilot-scale Decolorizing Ultrafiltration - Electrodialysis (DUFM-ED) system for mutual separation and valorization of organic and inorganic nutrients from BS to obtain concentrates of organic macromolecules (OMs), ammonium (NH4+), and potassium (K+). The hybrid system has been successfully implemented in a project of treating 200 tons of biogas slurry per day in Funan, China. The results showed that DUFM achieved 80 % retention of OMs with a five-fold concentration factor (CF), while ED enabled recovery rates exceeding 90 % for both NH4+ and K+, also at five-fold concentration. The process exhibited remarkable anti-fouling characteristics with 84.11 % flux recovery after cleaning, coupled with low specific energy consumption (8.7 kWh·m−3). Techno-economic assessment revealed substantial benefits, generating approximately 1.41 $·m−3 economic value while achieving carbon reduction of 1.62 kgCO2·m−3. This integrated approach establishes a sustainable benchmark for nutrient recycling, offering a viable pathway toward circular economy implementation in the biogas industry through its demonstrated operational efficiency, economic viability, and environmental benefits.